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Serum Separator Gel: Principles and Applications in Laboratory Medicine

 

Blood and its ingredients:

Blood testing is one of the most common methods for measuring physiological indicators and assessing human health.

For a clearer grasp of this concept, let’s review three important blood-related definitions and know more about its key components:

Blood: A mixture of blood cells (including red blood cells, white blood cells, and platelets), proteins (such as albumin, globulin, fibrinogen, etc.), glucose, mineral ions, hormones, and waste products

Plasma: The liquid portion of blood containing all components except blood cells

Serum: Obtained by separating the clotted components (including blood cells and coagulation proteins like fibrinogen) from whole blood

 

Serum, the optimal medium for diagnostic test:

Most diagnostic tests are performed on blood serum due to its:

  1. Limited interference with test results
  2. Stable composition which remains consistent over time compared to other blood components

    Thus, developing an effective method to isolate serum—without altering its integrity and ensuring complete separation until testing—is critical.

 

The Separation Process:

After blood is collected in test tubes, samples are left to clot. The samples are then centrifuged to separate the clot from the serum.

 

How SSG Works:

The SSG is pre-injected into blood collection tubes during assembly, where it settles at the bottom of the tube. During centrifuge process, the SSG moves from the bottom and positions itself at the interface between the serum and the clotted blood. The resulting impervious layer, with serum collected above it, enables clean serum extraction for diagnostic tests.

 

Key Requirements for an Effective SSG:

1- Density: intermediate between serum and blood cells

2- Inertness: must neither absorb nor release substances into the serum, and must not chemically interact with it

3- Sterilization resistance: Must withstand gamma radiation (used for tube sterilization)

4- Efficiency : Should achieve separation at low centrifuge speed and short duration

 

    Jav-add 01001 – Jav Afzooneh Avar SSG product

 

Jav-add 01001 meets all four requirements above. Its unique formulation is compatible with both vacuum and non-vacuum tubes, and its performance is validated in clinical and laboratory settings.

 Jav-add 01001 Advantages:

  • Precision: Rapid, clear serum separation
  • Customizability: Our R&D team can adjust gel properties to meet specific tube manufacturers’ needs
  • Ease of use: Optimized for seamless injection into tubes during production

Blood Serum Separating Gel


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